Fabrication of nanoemulsions by high-pressure valve homogenization

Andreas Håkansson

Research output: Chapter in Book/Report/Conference proceedingChapter in book

Abstract

High-pressure valve homogenization is a standard technique for nanoemulsion formation in low-viscosity formulations. It is applied extensively in industrial applications and in academic research. This chapter summarizes the scientific-based knowledge in terms of principal mechanisms of operation and practical applicability of the methodology. It is concluded that high-pressure valve homogenization has many advantages in producing nanoemulsions; the technique is mature and allows for continuous production and for production in various scales. However, the technique also has limitations. The thermodynamic efficiency is low, giving rise to high energy cost, and a substantial temperature rises in the product. The high pressures required for nanoemulsion formation have also been reported to cause overprocessing, which results in an additional limitation.

Original languageEnglish
Title of host publicationNanoemulsions
Subtitle of host publicationformulation, applications, and characterization
EditorsSeid Mahdi, David Julian
Place of PublicationStockholm
PublisherElsevier
Pages175-206
Number of pages31
ISBN (Print)978-0-12-811838-2
DOIs
Publication statusPublished - 2018

Swedish Standard Keywords

  • Natural sciences (1)

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