Immune suppression of the echinoderm Asterias rubens (L.) following long-term ocean acidification

Bodil Hernroth, Susanne Baden, Mike Thorndyke, Sam Dupont

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    61 Citations (Scopus)

    Abstract

    We compared effects of exposure to predict near-future (2100) ocean acidification (OA; pH 7.7) and normal seawater (Control; pH 8.1) on immune and stress responses in the adult sea star Asterias rubens. Analyses were made after one week and after six months of continuous exposure. Following one week exposure to acidified water, the pH of coelomic fluid was significantly reduced. Levels of the chaperon Hsp70 were elevated while key cellular players in immunity, coelomocytes. were reduced by approximately 50%. Following long-term exposure (six months) levels of Hsp70 returned to control values, whereas immunity was further impaired, evidenced by the reduced phagocytic capacity of coelomocytes and inhibited activation of p38 MAP-kinase. Such impacts of reduced seawater pH may have serious consequences for resistance to pathogens in a future acidified ocean.

    Original languageEnglish
    Pages (from-to)222-224
    Number of pages2
    JournalAquatic Toxicology
    Volume103
    Issue number3-4
    DOIs
    Publication statusPublished - 2011

    Swedish Standard Keywords

    • Biological Sciences (106)

    Keywords

    • CO(2)
    • Immunity
    • Marine
    • Ocean acidification
    • Stress indicators
    • celomocytes
    • hsp70
    • invertebrates
    • regeneration
    • seawater acidification

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