Improved general and oral health in diabetic patients by an Okinawan-based Nordic diet: a pilot study

Helene Holmer, Cecilia Widén, Viveca Wallin Bengtsson, Michael Coleman, Björn Wohlfart, Stig Steen, Rutger G Persson, Klas Sjöberg

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


Periodontal disease, periodontitis as well as the preceding gingivitis, has been associated with both obesity and diabetes. Studies have shown that diet changes can lead to a lower incidence of such inflammation. The aim of the present case series over four weeks was to study the effects on medical and dental conditions in patients with type 2 diabetes of the consumption of the Okinawan-based Nordic Diet (OBND®). Medical and dental examinations were performed to estimate the general health and gingivitis/periodontitis. Serum cytokine levels were assessed using Luminex technology. Eight of ten study participants completed the study. All participants lost weight (p = 0.012). Six out of seven that were treated with insulin could reduce their insulin intake after two weeks with OBND®. The reduction was about 16 units which corresponds to a 34% relative reduction compared to the starting point (range 15⁻63%). Fasting blood glucose values fell (p = 0.035). Hemoglobin A1c (HbA1c) (p = 0.01), triglycerides (p = 0.05), and low-density lipoprotein (LDL) (p = 0.05) were also reduced. Bleeding on probing changed from ~28% before any dietary changes to ~13% after two weeks with OBND® (p = 0.01). The reduction in gingival bleeding was as substantial as might be expected from one session of professional tooth cleaning. Markers of inflammation were also reduced. The OBND® thus showed significant promise in alleviating the impact of diabetes on dental as well as general health.

Original languageEnglish
JournalInternational Journal of Molecular Sciences
Issue number7
Publication statusPublished - 2018

Swedish Standard Keywords

  • Dentistry (30216)


  • bleeding on probing
  • clinical study
  • cytokines
  • diet
  • metabolic disorder
  • oral health


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