Longitudinal evaluation of periodontitis and development of cognitive decline among older adults

Helena Nilsson, Johan Sanmartin Berglund, Stefan Renvert

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)


AIM: to determine whether having periodontitis is associated with cognitive decline among older adults.

MATERIAL AND METHODS: A prospective population study of older adults, Swedish National Study on Ageing and Care, (SNAC) provided repeated registrations of cognitive functions. Cognitive decline was defined as ≥ 3-points deterioration from a predetermined level at baseline, using the Mini-Mental State Examination (MMSE). Between 2001 and 2003, 715 individuals had a medical as well as a clinical and radiographic dental examination. The individuals were re-examined after 6 years. Periodontitis was defined as ≥ 4mm bone loss at ≥ 30% of tooth sites. Social variables were captured from questionnaires.

RESULTS: The multivariate logistic regression analysis demonstrated a statistically significant association between prevalence of periodontitis and cognitive decline after adjustments of confounding factors of importance.

CONCLUSIONS: A history of periodontitis may be of importance for cognitive functions among older adults. This article is protected by copyright. All rights reserved.

Original languageEnglish
Pages (from-to)1142-1149
Number of pages7
JournalJournal of Clinical Periodontology
Issue number10
Publication statusPublished - 2018

Swedish Standard Keywords

  • Dentistry (30216)


  • Neurocognitive disorders
  • epidemiology
  • inflammation
  • older adults
  • periodontal diseases


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