The Gothenburg H70 Birth cohort study 2014-16: design, methods and study population.

Therese Rydberg Sterner, Felicia Ahlner, Kaj Blennow, Synneve Dahlin-Ivanoff, Hanna Falk, Lena Havstam Johansson, Maria Hoff, Mathias Holm, Helena Hörder, Tina Jacobsson, Boo Johansson, Lena Johansson, Jürgen Kern, Silke Kern, Alejandra Machado, Madeleine Mellqvist Fässberg, Johan Nilsson, Mats Ribbe, Elisabet Rothenberg, Lina RydénAndré Sadeghi, Simona Sacuiu, Jessica Samuelsson, Robert Sigström, Johan Skoog, Valgeir Thorvaldsson, Margda Waern, Eric Westman, Hanna Wetterberg, Henrik Zetterberg, Madeleine Zetterberg, Anna Zettergren, Svante Östling, Ingmar Skoog

Research output: Contribution to journalArticlepeer-review

38 Citations (Scopus)

Abstract

To improve health care for older persons, we need to learn more about ageing, e.g. identify protective factors and early markers for diseases. The Gothenburg H70 Birth Cohort Studies (the H70 studies) are multidisciplinary epidemiological studies examining representative birth cohorts of older populations in Gothenburg, Sweden. So far, six birth cohorts of 70-year-olds have been examined over time, and examinations have been virtually identical between studies. This paper describes the study procedures for the baseline examination of the Birth cohort 1944, conducted in 2014-16. In this study, all men and women born 1944 on specific dates, and registered as residents in Gothenburg, were eligible for participation (n = 1839). A total of 1203 (response rate 72.2%; 559 men and 644 women; mean age 70.5 years) agreed to participate in the study. The study comprised sampling of blood and cerebrospinal fluid, psychiatric, cognitive, and physical health examinations, examinations of genetics and family history, use of medications, social factors, functional ability and disability, physical fitness and activity, body composition, lung function, audiological and ophthalmological examinations, diet, brain imaging, as well as a close informant interview, and qualitative studies. As in previous examinations, data collection serves as a basis for future longitudinal follow-up examinations. The research gained from the H70 studies has clinical relevance in relation to prevention, early diagnosis, clinical course, experience of illness, understanding pathogenesis and prognosis. Results will increase our understanding of ageing and inform service development, which may lead to enhanced quality of care for older persons.

Original languageEnglish
Pages (from-to)191-209
Number of pages18
JournalEuropean Journal of Epidemiology
Volume34
Issue number2
DOIs
Publication statusPublished - 2019

Swedish Standard Keywords

  • Public Health, Global Health, Social Medicine and Epidemiology (30302)

Keywords

  • Ageing
  • Birth cohort
  • H70 study
  • Health
  • Population sample
  • Study design

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