Evaluation of skin reactions during proton beam radiotherapy: patient-reported versus clinician-reporte

Marie-Louise Möllerberg, Ulrica Langegård, Birgitta Johansson, Emma Ohlsson-Nevo, Per Fransson, Karin Ahlberg, Petra Witt-Nyström, Katarina Sjövall

Forskningsoutput: TidskriftsbidragArtikelPeer review

Sammanfattning

Background: Skin reaction is a common side-effect of radiotherapy and often only assessed as clinician-reported outcome (CRO). The aim was to examine and compare patient-reported outcome (PRO) of skin reactions with CRO for signs of acute skin reactions for patients with primary brain tumour receiving proton beam radiotherapy (PBT). A further aim was to explore patients' experiences of the skin reactions.

Methods: Acute skin reactions were assessed one week after start of treatment, mid-treatment and end of treatment among 253 patients with primary brain tumour who underwent PBT. PRO skin reactions were assessed with the RSAS and CRO according to the RTOG scale. Fleiss' kappa was performed to measure the inter-rater agreement of the assessments of skin reactions.

Results: The results showed a discrepancy between PRO and CRO acute skin reactions. Radiation dose was associated with increased skin reactions, but no correlations were seen for age, gender, education, occupation, other treatment or smoking. There was a poor agreement between patients and clinicians (κ = -0.016) one week after the start of PBT, poor (κ = -0.045) to (κ = 0.396) moderate agreement at mid treatment and poor (κ = -0.010) to (κ = 0.296) moderate agreement at end of treatment. Generally, patients' symptom distress toward skin reactions was low at all time points.

Conclusion: The poor agreement between PRO and CRO shows that the patient needs to be involved in assessments of skin reactions for a more complete understanding of skin reactions due to PBT. This may also improve patient experience regarding involvement in their own care.

OriginalspråkEngelska
Sidor (från-till)11-17
Antal sidor7
TidskriftTechnical innovations & patient support in radiation oncology
Volym19
DOI
StatusPublicerad - 2021

Nationell ämneskategori

  • Hälsovetenskap (303)
  • Cancer och onkologi (30203)

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