@article{7fc1f7b99eb3428f9327c3079387b78a,
title = "Immunohistochemical analyses of phosphatases in childhood B-cell lymphoma: Lower expression of PTEN and HePTP and higher number of positive cells for nuclear SHP2 in B-cell lymphoma cases compared to controls",
abstract = "Although many pediatric B-cell lymphoma patients are being cured today, much is still unknown about the pathogenesis of this disease. Protein tyrosine phosphatases are involved in the control of survival, growth, and differentiation of cells. The authors have analyzed 26 pediatric B-cell lymphoma cases for the expression of a panel of phosphatases and report a statistically significant lower expression intensity of PTEN and HePTP and higher nuclear SHP2 expression in B-cell lymphoma cases compared to lymphoid tissue. Knowledge about the expression of key regulatory proteins in pediatric B-cell lymphomas is necessary for revealing the complex molecular background of this disease.",
keywords = "Burkitt, Immunohistochemistry, Lymphoma, Pediatric, Protein tyrosine phosphatase",
author = "Marie Fridberg and Sofia Kjellstr{\"o}m and Lola Anagnostaki and Ingela Skogvall and Tomas Mustelin and Thomas Wiebe and Persson, {Jenny L.} and Michael Dictor and Wingren, {Anette Gj{\"o}rloff}",
note = "Funding Information: The authors thank Elise Nilsson for invaluable technical assistance. This work was supported by grants from the American Cancer Society for technology transfer, the Swedish Childrens Cancer Foundation, the Alfred {\"O}sterlund Foundation, the Magnus Bergvall Foundation, the Medical Faculty of Lund, Svenska L{\"a}kares{\"a}llskapet, the Siv-Inger and Per-Erik Andersson Foundation, the Berta Kamprad Foundation, the Cancer Foundation at Malm{\"o} University Hospital, and the Ellen Bachrach{\textquoteright}s Children{\textquoteright}s Cancer Foundation of Haematology.",
year = "2008",
month = aug,
doi = "10.1080/08880010802237054",
language = "English",
volume = "25",
pages = "528--540",
journal = "Pediatric Hematology and Oncology",
issn = "0888-0018",
publisher = "Informa Healthcare",
number = "6",
}