TY - JOUR
T1 - Periodontitis related to cardiovascular events and mortality
T2 - a long-time longitudinal study
AU - Wallin Bengtsson, Viveca
AU - Persson, Rutger G
AU - Berglund, Johan Sanmartin
AU - Renvert, Stefan
N1 - Funding Information:
We acknowledge the contribution by Associate Professor Rigmor Persson (REP), University of Washington, who analyzed the radiographs. We also want to acknowledge Ms. Ingrid Jonasson, Blekinge Institute of Technology, Karlskrona, Sweden, who collected the clinical dental data and Ms. Johanna Renvert, University of Kristianstad, for data management. We are specifically grateful to the study participants. The study was accomplished within the context of the Swedish National Graduate School for Competitive Science on Aging and Health (SWEAH). The Ministry of Health and Social Affairs, Sweden; the participating county councils, municipalities, and university departments; and the Swedish National Study on Aging and Care (SNAC) (www. snac.org) supported the study. The study was also supported by the Research Foundation at Kristianstad University, Sweden.
Funding Information:
We acknowledge the contribution by Associate Professor Rigmor Persson (REP), University of Washington, who analyzed the radiographs. We also want to acknowledge Ms. Ingrid Jonasson, Blekinge Institute of Technology, Karlskrona, Sweden, who collected the clinical dental data and Ms. Johanna Renvert, University of Kristianstad, for data management. We are specifically grateful to the study participants. The study was accomplished within the context of the Swedish National Graduate School for Competitive Science on Aging and Health (SWEAH). The Ministry of Health and Social Affairs, Sweden; the participating county councils, municipalities, and university departments; and the Swedish National Study on Aging and Care (SNAC) (www. snac.org ) supported the study. The study was also supported by the Research Foundation at Kristianstad University, Sweden.
Publisher Copyright:
© 2021, The Author(s).
PY - 2021
Y1 - 2021
N2 - OBJECTIVE: The present study assessed if individuals ≥ 60 years of age with periodontitis are more likely to develop stroke or ischemic heart diseases, or at a higher risk of death for 17 years.MATERIAL AND METHODS: At baseline individuals ≥ 60 received a dental examination including a panoramic radiograph. Periodontitis was defined as having ≥ 30% sites with ≥ 5-mm distance from the cementoenamel junction to the marginal bone level. Medical records were annually reviewed from 2001 to 2018. Findings from the medical records identifying an ICD-10 code of stroke and ischemic heart diseases or death were registered.RESULTS: Associations between periodontitis and incidence of ischemic heart disease were found in this 17-year follow-up study in all individuals 60-93 years (HR: 1.5, CI: 1.1-2.1, p = 0.017), in women (HR: 2.1, CI: 1.3-3.4, p = 0.002), and in individuals 78-96 years (HR: 1.7, CI: 1.0-2.6, p = 0.033). Periodontitis was associated with mortality in all individuals (HR: 1.4, CI: 1.2-1.8, p = 0.002), specifically in men (HR: 1.5, CI: 1.1-1.9, p = 0.006) or in ages 60-72 years (HR: 2.2, CI: 1.5-3.2, p = 0.000). Periodontitis was more prevalent among men (OR: 1.8, CI: 1.3-2.4, p = 0.000).CONCLUSIONS: Individuals with periodontitis have an increased risk for future events of ischemic heart diseases and death.CLINICAL RELEVANCE: Improving periodontal health in older individuals may reduce overall mortality and ischemic heart diseases. Both dental and medical professionals should be aware of the associations and ultimately cooperate.
AB - OBJECTIVE: The present study assessed if individuals ≥ 60 years of age with periodontitis are more likely to develop stroke or ischemic heart diseases, or at a higher risk of death for 17 years.MATERIAL AND METHODS: At baseline individuals ≥ 60 received a dental examination including a panoramic radiograph. Periodontitis was defined as having ≥ 30% sites with ≥ 5-mm distance from the cementoenamel junction to the marginal bone level. Medical records were annually reviewed from 2001 to 2018. Findings from the medical records identifying an ICD-10 code of stroke and ischemic heart diseases or death were registered.RESULTS: Associations between periodontitis and incidence of ischemic heart disease were found in this 17-year follow-up study in all individuals 60-93 years (HR: 1.5, CI: 1.1-2.1, p = 0.017), in women (HR: 2.1, CI: 1.3-3.4, p = 0.002), and in individuals 78-96 years (HR: 1.7, CI: 1.0-2.6, p = 0.033). Periodontitis was associated with mortality in all individuals (HR: 1.4, CI: 1.2-1.8, p = 0.002), specifically in men (HR: 1.5, CI: 1.1-1.9, p = 0.006) or in ages 60-72 years (HR: 2.2, CI: 1.5-3.2, p = 0.000). Periodontitis was more prevalent among men (OR: 1.8, CI: 1.3-2.4, p = 0.000).CONCLUSIONS: Individuals with periodontitis have an increased risk for future events of ischemic heart diseases and death.CLINICAL RELEVANCE: Improving periodontal health in older individuals may reduce overall mortality and ischemic heart diseases. Both dental and medical professionals should be aware of the associations and ultimately cooperate.
KW - Epidemiology
KW - Ischemic heart disease
KW - Mortality
KW - Periodontitis
KW - Follow-Up Studies
KW - Humans
KW - Middle Aged
KW - Risk Factors
KW - Male
KW - Periodontitis/complications
KW - Incidence
KW - Adolescent
KW - Female
KW - Stroke/epidemiology
KW - Aged
KW - Longitudinal Studies
U2 - https://doi.org/10.1007/s00784-020-03739-x
DO - https://doi.org/10.1007/s00784-020-03739-x
M3 - Article
C2 - 33506429
SN - 1432-6981
VL - 25
SP - 4085
EP - 4095
JO - Clinical Oral Investigations
JF - Clinical Oral Investigations
ER -