TY - JOUR
T1 - Recent Advances in Molecularly Imprinted Polymers and Their Disease-Related Applications
AU - Cabaleiro Lago, Celia
AU - Hasterok, Sylwia
AU - Gjörloff Wingren, Anette
AU - Tassidis, Helena
PY - 2023/10/24
Y1 - 2023/10/24
N2 - Molecularly imprinted polymers (MIPs) and the imprinting technique provide polymeric material with recognition elements similar to natural antibodies. The template of choice (i.e., the antigen) can be almost any type of smaller or larger molecule, protein, or even tissue. There are various formats of MIPs developed for different medical purposes, such as targeting, imaging, assay diagnostics, and biomarker detection. Biologically applied MIPs are widely used and currently developed for medical applications, and targeting the antigen with MIPs can also help in personalized medicine. The synthetic recognition sites of the MIPs can be tailor-made to function as analytics, diagnostics, and drug delivery systems. This review will cover the promising clinical applications of different MIP systems recently developed for disease diagnosis and treatment.
AB - Molecularly imprinted polymers (MIPs) and the imprinting technique provide polymeric material with recognition elements similar to natural antibodies. The template of choice (i.e., the antigen) can be almost any type of smaller or larger molecule, protein, or even tissue. There are various formats of MIPs developed for different medical purposes, such as targeting, imaging, assay diagnostics, and biomarker detection. Biologically applied MIPs are widely used and currently developed for medical applications, and targeting the antigen with MIPs can also help in personalized medicine. The synthetic recognition sites of the MIPs can be tailor-made to function as analytics, diagnostics, and drug delivery systems. This review will cover the promising clinical applications of different MIP systems recently developed for disease diagnosis and treatment.
KW - biomarker
KW - diagnostics
KW - medical applications
KW - molecularly imprinted polymers
KW - sensors
U2 - 10.3390/polym15214199
DO - 10.3390/polym15214199
M3 - Review article
SN - 2073-4360
VL - 15
SP - 1
EP - 20
JO - Polymers
JF - Polymers
IS - 21
M1 - 4199
ER -