Simultaneous determination of endogenous steroid hormones in human and animal plasma and serum by liquid or gas chromatography coupled to tandem mass spectrometry

Jonas Abdel–Khalik, Erland Björklund, Martin Hansen

Forskningsoutput: TidskriftsbidragArtikelPeer review

Sammanfattning

Analytical methodologies based on liquid or gas chromatography coupled to tandem mass spectrometry for the simultaneous determination of two or more endogenous steroid hormones in human and animal plasma and serum has received increased attention the last few years. Especially in the clinical setting steroid profiling is of major importance in disease diagnostics. This paper discusses recent findings in such multi-steroid hormone procedures published from 2001 to 2012. The aim was to elucidate possible relationships between chosen analytical technique and the obtained analyte sensitivity for endogenous steroid hormones. By evaluating the success, at which the currently applied techniques have been utilized, more general knowledge on the field is provided. Furthermore the evaluation provides directions in which future studies may be interesting to conduct.

OriginalspråkEngelska
Sidor (från-till)59-77
Antal sidor18
TidskriftJournal of chromatography. B
Volym928
UtgåvaJune
DOI
StatusPublicerad - 2013

Nationell ämneskategori

  • Biologi (106)

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